Detection Kit for hepatitis b virus pre-s2 antigen
(Enhanced chemiluminescence immunoassay)
【Product Name】 Detection Kit for hepatitis b virus pre-s2 antigen (Enhanced chemiluminescence immunoassay)
【registration certificate number】 国械注准20163401107
This product is used for the qualitative detection of hepatitis B virus pre-S2 antigen in human serum in vitro.
Hepatitis B virus (HBV) outer membrane proteins include S, pre-S1 and pre-S2. The pre-S2 antigen (PreS2) is a hepatitis B virus (HBV) capsid protein that has been found and identified in recent years and coexists with the hepatitis B virus surface antigen (HBsAg) on the outer capsid of HBV. Some studies have shown that Pre-S2 antigen can appear in the serum of patients with acute hepatitis B and disappeared before the disappearance of HBsAg, which can indicate the patient's intrahepatic HBV replication and the highly contagious of serum.
The kit uses double antibody sandwich method. Microplate was pre-coated with Hepatitis B virus pre-S2 monoclonal antibody, add the sample to be tested, then add horseradish peroxidase-labeled anti-HBS monoclonal antibody, if there are antigen to be detected, the complex antibody - antigen -enzyme labeled antibody will form. Add luminescent substrate and HRP to generate luminescent signal.
Typical Symptoms:
1.Systemic performance: Patients often feel fatigue, fatigue, may be accompanied with mild fever and so on. Insomnia, dreams. may be related to this disease.
2. Gastrointestinal manifestations: abnormal liver function, reduced bile secretion, often appear loss of appetite, nausea, tired of the oil, abdominal discomfort, bloating and so on.
3. Jaundice: bilirubin excreted from the urine, urine color turns yellow, is the earliest performance of jaundice. Bilirubin concentration in the blood continues to increase, can cause eye, skin yellow dye.
4. Liver pain: chronic hepatitis B generally do not have severe pain. Some patients may have discomfort, pain, tenderness or percussion pain of right upper or right quarter rib.
5.Hepatosplenomegaly: due to inflammation, congestion, edema, cholestasis, patients often have hepatomegaly. Early acute hepatitis or chronic hepatitis, spleen has no significant enlargement, portal hypertension, splenic congestion, can cause splenomegaly.
Other Symptoms:
Men may have erectile dysfunction; women may appear symmetrical or asymmetrical breast hyperplasia, swelling and breast development, even misdiagnosed as breast cancer, menstrual disorders, amenorrhea, loss of libido and so on.
Clinical laboratory, physical examination center.